柴欣副研究员

发布日期:2025-01-04 14:46    点击次数:164

大学开始受教育经历:•     2001年~2005年,天津大学,药学院,药学专业学士•     2005年~2007年,天津大学,药学院,生药学专业硕士•     2007年~2010年,天津大学,药学院,应用化学专业博士 •     2010年~2013年,天津中医药大学,中药学博士后•     2013年~今,天津中医药大学,副研究员。目前正在进行的科研项目包括:基于整合组学技术的血府逐瘀汤从“菌”论治的生物学基础研究,六神曲发酵过程中化学成分的变化规律研究,祛风止痛胶囊化学物质及质量分析研究等。2005年至今一直从事药用植物的化学成分分离与结构鉴定、生物活性成分筛选、中药质量控制的研究。主持和参与了国家自然科学基金、国家重大新药创制科技重大专项、天津市科技计划项目等重大科研项目;以第一作者或通讯作者发表SCI论文15篇,中文核心期刊论文9篇;以第一发明人授权发明专利2项。2015年入选天津市“131”创新型人才培养工程第三层次人选,2020年入选天津市高校“中青年骨干创新人才培养计划”。以第11完成人参加课题《基于雌激素样作用的中药物质基础及作用机理差异性研究》,并获得了教育部颁发的科技成果以及科学技术进步一等奖。代表性论文:(1) Jing Zhang, Danni Wang, Xiaoyu Zhang, Jing Yang,   Xin Chai*,Yuefei Wang*. Application of “spider-web” mode in discovery and   identification of Q-markers from Xuefu Zhuyu capsule. Phytomedicine, 2020,   77:153273.(2) Xinhui Wang, Rui Li, Xiangyue Liu, Shan Huang,   Bin Li, Honglei Wang, Xin Chai*,Yuefei Wang*. Study on characteristics of   biflavanones distribution in Garcinia kola seeds and identification of   compounds in gum resin exuded from fresh slices. Journal of Pharmaceutical   and Biomedical Analysis 2020, 190 (113512): 1-9(3) Hui-Juan Yu#, Jing Yang#*, Jia-Min Ding, Ying   He, Zhen-Zuo Jiang, Xin Chai*, Yue-Fei Wang. Stability study and   identification of degradation products of caffeoylgluconic acid derivatives   from Fructus Euodiae. Molecules 2018, 23, 1975 (4) Cong-Cong Li, Teng-Long Wang, Zhong-Qun Zhang,   Wen-Qiang Yang, Yue-Fei Wang, Xin Chai*, Chun-Hua Wang*, Zheng Li.   Phytochemical and pharmacological studies on the genus Psoralea: a mini   review. Evidence-Based Complementary and Alternative Medicine 2016, 8108643:   1-17(5) Xin Chai#*, Long-Fei Du#, Jing Yang, Zhen-Zuo   Jiang, Long Yang, Yue-Fei Wang, Yan Zhu. Simultaneous determination of eight   constituents in fruits of Rubus chingii by UPLC. Chinese Herbal Medicines   2016, 8(3): 280-285(6) Jie Li#, Long-Fei Du#, Ying He, Long Yang,   Yuan-Yuan Li, Yue-Fei Wang, Xin Chai*, Yan Zhu, Xiu-Mei Gao. Chemical   constituents and biological activities of plants from the genus Rubus.   Chemistry & Biodiversity 2015, 12: 1809-1847(7) Ying He, Jie Li, Hong-Hua Wu, Xin Chai*, Jing   Yang*, Yue-Fei Wang, Peng Zhang, Yan Zhu, Xiu-Mei Gao. A new caffeoylgluconic   acid derivative from the nearly ripe fruits of Evodia rutaecarpa. Natural   Product Research 2015, 29(13): 1243-1248(8) Xiao-Long Zhang, Jie Sun, Hong-Hua Wu, Ya-Kun   Jing, Xin Chai*, Yue-Fei Wang. A new indoloquinazoline alkaloidal glucoside   from the nearly ripe fruits of Evodia rutaecarpa. Natural Product Research   2013, 27(20): 1917-1921(9) Xin Chai, Shan-Shan Li, Lin Zhu, Yue-Fei Wang,   Xiu-Mei Gao*. Chemical constituents of the roots of Trichosanthes kirilowii.   Chemistry of Natural Compounds 2014, 50(5): 965-967(10) Xin Chai, Yan-Fang Su*, Shi-Lun Yan, Xiong   Huang. Chemical constituents of the roots of Triosteum pinnatifidum.   Chemistry of Natural Compounds 2014, 50(6): 1149-1152(11) Xin Chai, Yue-Fei Wang*, Yan-Fang Su, Abdulai   J. Bah, Li-Min Hu, Yue Gao, Xiu-Mei Gao*. A rapid ultra performance liquid   chromatography-tandem mass spectrometric method for the qualitative and   quantitative analysis of ten compounds in Eucommia ulmodies Oliv. Journal of   Pharmaceutical and Biomedical Analysis 2012, 57: 52-61

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